Chan Gailey is a man of few words.

When those few words hint strongly at the possibility of a running back who’s just 85 yards behind the league’s leading rusher being out for the season, that’s bad. It’s the kind of bad that makes you believe in the karma police, and that they’re working to quickly correct their mistake from earlier this year that saw the Bills beat New England and Philadelphia, and start 4-1.

Fred Jackson left Buffalo’s Week 11 loss to Miami in the second quarter with a calf injury. He’s already been ruled out for a divisional showdown against the Jets this weekend, a crucial game for the Bills as they try to keep their slim wild card hopes alive.

Gailey didn’t sound too optimistic about Jackson’s chances of playing in the other five games remaining in the season either.

From the Buffalo News:

“Fred’s not good, and I know he’ll miss this one,” Gailey said. “Then we’ll have to decide what happens from there.”

Asked if there was a chance Jackson could be back before the end of the season, Gailey said: “I don’t know about that. We’ll have to wait and see.”

The eternal optimist views this as C.J. Spiller’s opportunity to finally break out.

Jackson has averaged 5.5 yards per carry with six rushing touchdowns and six 100-yard games, numbers that have nearly eliminated Spiller’s presence in Buffalo’s offense. His 63-yard outburst on just four carries in Week 2 is very much an anomaly this season, and if we exclude that game the second-year RB is getting a meager 1.5 carries for just 4.7 yards per game.

Although the Bills have attempted to utilize Spiller’s explosiveness in the passing game, there’s also been two games in which he didn’t receive any carries, and four if we include his rookie season.

The pessimist and realist will see an offense that’s mustered just 26 points over a three-game losing streak, and a quarterback who has lost the support of his primary running back while his early-season accuracy is turning into late-season inaccuracy. They’ll then gaze back fondly on the memories from a few months ago when Bills fans were dressing up as clowns and yelling something crazy about the playoffs.

UPDATE: The Bills have officially placed Jackson on injured reserve and signed Tashard Choice to fill his spot on the roster.