Buffalo Bills v San Francisco 49ers

When there's nothing left to lose.

SAN FRANCISCO, CA – OCTOBER 7: Head coach Chan Gailey of the Buffalo Bills looks at his play chart during a game against the San Francisco 49ers in the second quarter on October 7, 2012 at Candlestick Park in San Francisco, California. The 49ers won 45-3. (Photo by Brian Bahr/Getty Images)